Can i use lotrimin af for a yeast infection




















In clinical trials, vaginal use during the second and third trimesters in humans has not resulted in any adverse effects; there are no adequate and well-controlled studies of pregnant women during the first trimester. Use topical or vaginal clotrimazole during the first trimester of pregnancy only if clearly indicated. Clotrimazole oral lozenges are classified as FDA pregnancy category C. There are no adequate and well-controlled studies of oral clotrimazole in pregnant women.

No teratogenic effects have been demonstrated in animal studies at doses up to times the human dose; however, doses of times the adult human dose were embryotoxic in rats and mice. Use oral clotrimazole lozenges during pregnancy only if the potential benefit justifies the potential risk to the fetus. The use of clotrimazole during breast-feeding has not been studied.

Topical application is not expected to result in significant maternal absorption, and should not be of significant risk to a breast-feeding infant. Instruct mothers not to apply clotrimazole topically to the breast during times of breast-feeding. The oral troches may be absorbed systemically, but significant infant exposure is unknown and expected to be low; observe the infant for any possible adverse effects.

Fluconazole, miconazole, and nystatin may be potential alternatives to consider, though site of infection, local susceptibility patterns, and specific microbial susceptibility should be assessed before choosing an alternative agent. Consider the benefits of breast-feeding, the risk of potential infant drug exposure, and the risk of an untreated or inadequately treated condition. If a breast-feeding infant experiences an adverse effect related to a maternally ingested or administered drug, health care providers are encouraged to report the adverse effect to the FDA.

Patients who are using intravaginal clotrimazole preparations are recommended to abstain from sexual intercourse during the treatment course.

Contraceptive devices, including condoms, diaphragms, and cervical caps can be damaged while using these products, and may lead to contraceptive failures.

Although clotrimazole may be used during menstruation, instruct patients not to use tampons. Clotrimazole should be used with caution in patients with azole antifungals hypersensitivity. Hypersensitivity reactions may be due to the various vehicles present in the different clotrimazole formulations.

Clotrimazole may have a cross sensitivity with other azole derivatives. Self-administration of clotrimazole for longer than 7 days is contraindicated. If there is no improvement in the condition after 3 days, or if the condition persists after 7 days, the patient should discontinue clotrimazole therapy and consult a physician.

Some patients should not use non-prescription clotrimazole products without the supervision of a health care professional; patients with immunosuppression, undergoing chemotherapy, diabetes mellitus, or human immunodeficiency virus HIV infection should discuss use of these products with their health care professional prior to self-treatment. Such symptoms may be an indication of another vaginal infection or pelvic inflammatory disease.

Avoid ocular exposure to clotrimazole; do not give by ophthalmic administration. If ocular exposure occurs, treat by immediate flushing the affected eye with cool, clean water.

Contact an ophthalmologist if eye irritation persists. Progesterone: Moderate Vaginal preparations of progesterone e.

Separate the times of administration to avoid the interaction. The manufacturers of Crinone and Prochieve indicate that other intravaginal products can be used as long as 6 hours has lapsed either before or after vaginal administration of progesterone. Endometrin is generally not recommended for use with other vaginal products e.

Like other azole antifungals, clotrimazole exerts its effect by altering the fungal cell membrane. Clotrimazole inhibits ergosterol synthesis by interacting with alpha demethylase, a cytochrome P enzyme that is necessary for converting lanosterol to ergosterol, an essential component of the membrane.

In contrast, amphotericin B binds to ergosterol after it is synthesized. Inhibition of ergosterol synthesis results in increased cellular permeability, causing leakage of cellular contents such as phosphorous-containing compounds and potassium. Clotrimazole does not appear to have the same activity upon human cholesterol synthesis.

Other antifungal effects of azole compounds have been proposed and include: inhibition of endogenous respiration, interaction with membrane phospholipids, and inhibition of transformation of yeasts to mycelial forms. As a treatment for infectious diarrhea, clotrimazole is thought to interfere with chloride and resulting fluid accumulation in epithelial cells lining the intestine.

Clotrimazole inhibits the movement of calcium and potassium ions across the cell membrane. This action may be responsible for in vitro and animal data demonstrating an antitumor effect of clotrimazole. This action may also explain why clotrimazole prevents the dehydration of the red blood cell in patients with sickle cell disease.

Clotrimazole inhibits the loss of intracellular potassium by blocking the ion transport pathway known as the Gardos channel. Small amounts absorbed are metabolized in the liver and excreted in the bile.

Transmucosal Route Clotrimazole oral lozenges are used for local treatment and are not significantly bioavailable. Concentrations persisting in saliva are believed to be due to clotrimazole binding to oral mucosa. Fungicidal concentrations persist in the vagina for up to 3 days after application. Though this surgical procedure is typically done on infants, it can be done safely on a man of any age.

Learn more: Circumcision ». Along with using the medicated cream, you should also practice good hygiene to help clear up any lingering infection. Factors such as diabetes and a suppressed immune system may contribute to your yeast infection risk.

If you have diabetes, work with your healthcare providers to make sure your blood sugar levels are well controlled. If you have a suppressed immune system, your doctor can recommend ways to help keep your immune system as healthy as possible. One of the potential complications of a penile yeast infection is balanitis.

Balanitis is an inflammation of the foreskin or head of the penis. Diabetes can increase your risk for balanitis.

Learn more: Balanitis ». It can also cause adhesions on the penis. The condition can be painful and make urinating more difficult. If untreated, balanitis can cause swollen and painful glands, as well as weakness and fatigue. A yeast infection may enter the bloodstream. This is known as candidemia or invasive candidiasis. This is most common in men who wait to receive treatment until the infection has spread beyond the penis. It is also more common in men with weakened immune systems.

This advanced form of a yeast infection is very serious. Oral antifungal medications may be needed for several weeks. In some cases, the drugs are administered intravenously. If your infection is treated early and responds well to antifungal medication, it can clear up within a week.

If you are sexually active, your partner should also be treated for a yeast infection to avoid re-infection. Your partner should be treated regardless of whether or not the infection was spread from them to you. If you get recurrent yeast infections and you can rule out causes such as hygiene and sexual contact, talk with your doctor about other possible causes. You may have an underlying health condition, such as diabetes. You can help prevent a penile yeast infection by avoiding sexual contact with a partner who has a yeast infection.

You should also avoid having sex with anyone while you have an active yeast infection. You could give the infection back to your partner, and the two of you could trade an infection back and forth. Penile yeast infections are uncommon.

They may result from poor hygiene or condomless sex with a partner who has a vaginal yeast infection. Symptoms include small white patches and redness on the skin and itchiness or burning. In most cases, topical antifungal ointments and creams can treat the infection.

Balanitis is swelling of the foreskin or head of the penis. Symptoms include redness, discharge, itchiness, and pain. See some examples and descriptions. Coconut oil is said to have many health benefits, such as aiding digestion and helping to balance your hormones. You may be familiar with…. Having an itch on or around your testicles or scrotum isn't uncommon.

Sweating in your groin after taking a walk can cause your testicles to itch more…. Urethritis is a condition in which the urethra, or the tube that carries urine from the bladder to outside the body, becomes inflamed and irritated. Scabies can cause an itchy rash on your genitals. A mite called Sarcoptes scabiei causes scabies.

You can only see these mites through a microscope…. Health Conditions Discover Plan Connect. Medically reviewed by Alana Biggers, M. What is a penile yeast infection? What are the symptoms of a penile yeast infection? What causes a penile yeast infection?



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